Profhilo vs Profhilo Structura: What’s the Difference and Which One’s Right for You?

By now, you’ve probably heard of Profhilo - the injectable skin booster dubbed everything from a “liquid facelift” to the “ultimate glow-up.” But recently, a new name has started gaining attention: Profhilo Structura.

If you're thinking…

Wait… is that better?

Do I need that instead?

Is it just marketing? - You're not alone.

Let’s walk through it clearly, so you can confidently decide what’s right for your skin.

What is Profhilo?

Profhilo is pure hyaluronic acid, injected just beneath the skin. It’s not a filler and it doesn’t add volume — instead, it spreads smoothly to hydrate, plump, and revitalise from within.

Think of it as a deep drink of water for skin that’s tired, dehydrated, or starting to show signs of ageing. It works wonders across the face, neck, and hands, and is a favourite among mums looking for subtle rejuvenation without change to facial shape.

Why patients love it:

  • Boosts deep hydration

  • Enhances elasticity and skin “bounce

  • Smooths and softens texture

  • Provides a gentle tightening effect

  • Leaves skin glowing — without looking “done

What is Profhilo Structura?

Structura is the more supportive sibling of Profhilo, designed to strengthen and rebuild deeper layers of the skin.

While still based on hyaluronic acid, its formulation allows it to sit deeper in the dermis, helping to address sagging, hollow areas, and loss of facial support.

Ideal if you’re noticing:

  • Loss of definition in the cheeks or jawline

  • Hollowing around temples or under the eyes

  • A general softening or sagging of facial contours

  • Skin that feels thinner or less resilient than before

Structura doesn’t just hydrate — it reinforces. It’s especially helpful in restoring firmness and improving collagen stimulation over time.

So... which one is right for me?

Instead of a table, here’s a simple side-by-side look at the most common skin concerns and the treatment that best supports them:

If your main concern is:
• Dryness or dullness → Go for Profhilo
• Loss of firmness or facial shape → Try Structura
• Skin looks tired and lacks glow → Start with Profhilo
• You’ve tried Profhilo and want deeper support → Step up to Structura
• Both skin texture and structure are changing → You may benefit from a combination

Many women in their late 30s to 50s choose a personalised blend of both to restore hydration and firmness in harmony.

Can they be used together?

Absolutely! & they often work even better as a duo.

In-clinic, we frequently combine Profhilo for skin texture and radiance, with Structura for lift and shape. This is especially popular with mums going through hormonal shifts, post-pregnancy changes, or natural collagen loss.

It’s a beautiful, regenerative approach that gives your skin what it needs at multiple levels without ever overdoing it.

What’s the downtime?

Both are minimal-downtime injectables. You may see small bumps or mild swelling at injection sites for a day or two, but you can usually return to your normal routine the same day.

Most clients schedule it midweek and are glowing by the weekend.

The takeaway?

  • Profhilo brings hydration, elasticity, and skin luminosity

  • Structura restores structure, strength, and definition

Used alone or together, they can completely change how your skin feels and how you feel in your skin.

Not sure where to start?

Let’s talk. I offer in-depth skin consultations to guide you toward the most supportive, effective plan for where you are now. Book a consultation at our Essex clinic and we’ll build a bespoke skin strategy that feels empowering, not overwhelming, and leaves you feeling lifted, radiant, and like you again.

Piril Sideras | Aesthetic Practitoner | Essex

Piril Sideras is the founder of Piril Sideras - Aesthetics & Skin Sanctuary, a luxury clinic in Waltham Abbey, Essex. As a prescribing pharmacist, she offers bespoke, non-surgical treatments focused on enhancing natural beauty. Her clinic is a serene, inclusive space prioritizing safety, innovation, and personalized care to help clients feel confident and radiant.

https://www.pirilsideras.com
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